產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-CDK5RAP2抗體產(chǎn)品質(zhì)量穩(wěn)定,實(shí)驗(yàn)效果明顯,貨期快,價(jià)格優(yōu)惠,歡迎垂詢訂購(gòu)!我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-CDK5RAP2抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹:
Rabbit Anti-CDK5RAP2
Cat. Number:
Anti-CDK5RAP2抗體KL-9076R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation Anti-CDK5RAP2抗體of a dimer that inhibits kinase activity. CDK5RAP2, also known as Centrosome-associated protein 215, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1. Expressed in placenta, liver, pancreas, heart, skeletal muscle, lung, brain and kidney, CDK5RAP2 associates with centrosomes throughout the cell cycle. Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, which is characterized by markedly reduced head size, brain weight and significant neurological deficits. There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events.
Also known as:
C48; CDK5 activator-binding protein C48; CDK5 regulatory subunit associated protein 2; CDK5 regulatory subunit-associated Anti-CDK5RAP2抗體protein 2; centrosomal protein 215 kDa; Centrosome-associated protein 215; CEP215; MCPH3; CK5P2_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, .
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Immunogen: KLH conjugated synthetic peptide derived from human CDK5RAP2.
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Predicted Molecular Weight: 215kDa.
Storage:
Shipped at 4℃, Store Anti-CDK5RAP2抗體at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200
Not yet tested in other applications.
Optimal working Anti-CDK5RAP2抗體dilutions must be determined by the end user.
Not yet tested in other applications.
Optimal working Anti-CDK5RAP2抗體dilutions must be determined by the end user.
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