国产一区二区三区久久精品-国产一区二区三区久久-国产一区二区三区精品视频-国产一区二区三区国产精品-国产一区二区三区高清-国产一区二区三区成人久久片

產品詳情
  • 產品名稱:重組人類單核細胞趨化蛋白-1 / CCL2蛋白

  • 產品型號:rHuMCP-1/CCL2
  • 產品廠商:KALANG
  • 產品文檔:
你添加了1件商品 查看購物車
簡單介紹:
重組人類單核細胞趨化蛋白-1 / CCL2蛋白與其它公司提供的重組蛋白不同,rHuMCP-1/CCL2蛋白產品為采用CFS的無細胞麥胚蛋白合成系統表達出來的重組蛋白,可表達出對細胞有毒性、易被蛋白酶降解的蛋白;并獲得具有良好的可溶性,并有翻譯后修飾、從而部分具有功能的蛋白.同時獨有的全自動蛋白純化技術則簡便高效,將蛋白純化過程中對蛋白的損傷降低到*小程度.重組人類單核細胞趨化蛋白-1 / CCL2蛋白(全長序列)產品可用于Western Blot驗證、抗體制備、蛋白檢測、ELISA等試驗中.
詳情介紹:

重組人類單核細胞趨化蛋白-1 / CCL2蛋白

Synonyms HC11, Monocyte chemoattractant protein 1, MCAF, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2
Species Human
Accession P13500
GeneID 6347
Source 重組人類單核細胞趨化蛋白-1 / CCL2蛋白Escherichia coli.
Molecular Weight Approximately 8.7 kDa, a single non-glycosylated polypeptide chain containing 76 amino acids.
Quantity 5μg/20μg/1000μg
AA Sequence QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT
Purity > 96 % by SDS-PAGE and HPLC analyses.
Biological Activity 重組人類單核細胞趨化蛋白-1 / CCL2蛋白Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl.
Endotoxin Less than 1 EU/μg of rHuMCP-1/CCL2 as determined by LAL method.
Reconstitution 重組人類單核細胞趨化蛋白-1 / CCL2蛋白We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Storage This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
重組人類單核細胞趨化蛋白-1 / CCL2蛋白
Reference 1. Carr MW, Roth SJ, Luther E, et al. 1994. Proc Natl Acad Sci U S A. 91:3652-6.
2. Yoshimura T, Yuhki N, Moore SK, et al. 1989. FEBS Lett. 244:487-93.
3. Furutani Y, Nomura H, Notake M, et al. 1989. Biochem Biophys Res Commun. 159:249-55.
4. Craig MJ, Loberg RD. 2006. Cancer Metastasis Rev. 25:611-9.
5. Conti P, Boucher W, Letourneau R, et al. 1995. Immunology. 86:434-40.
6. Bischoff SC, Krieger M, Brunner T, et al. 1992. J Exp Med. 175:1271-5.
7. Xia M, Sui Z. 2009. Expert Opin Ther Pat. 19:295-303.
8. Lloyd CM, Minto AW, Dorf ME, et al. 1997. J Exp Med. 185:1371-80.
Background CCL2, also named monocyte chemotactic protein-1 (MCP-1) and small inducible cytokine A2, is a small cytokine that belongs to the CC chemokine family. It is a monomeric polypeptide, with a molecular weight of approximately 13 kDa and it is anchored in the plasma membrane of endothelial cells by glycosaminoglycan side chains of proteoglycans. Research shows that CCR2 and CCR4 are two cell surface receptors that bind CCL2. CCL2 exhibits a chemotactic activity for monocytes and basophils. However, it does not attract neutrophils or eosinophils. CCL2 has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis and it may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. Mature human CCL2 shares 78-79 % a.a. identity with canine, porcine and equine CCL2, while mouse and rat express a form of CCL2 that is extended by 49 a.a. and shares only ~56 % a.a. identity within the common region.

標題:
內容:
聯系人:
聯系電話:
Email:
公司名稱:
聯系地址:
 
 
注:1.可以使用快捷鍵Alt+S或Ctrl+Enter發送信息!
2.如有必要,請您留下您的詳細聯系方式!

滬公網安備 31011702004399號

主站蜘蛛池模板: 粉嫩在线| 色综合婷婷 | 国产美女啪啪 | 一级一片一a一片 | 国产一区中文字幕 | 精品亚洲欧美高清不卡高清 | 好男人好手机视频在线影视 | 欧美亚洲一区二区三区 | 亚洲性久久久影院 | 四虎国产成人免费观看 | 国产一区二区三区免费看 | 国产成人亚洲精品乱码在线观看 | 国产在线干| www青青草原| 亚洲六月丁香色婷婷综合久久 | live 电视剧| 亚洲精品中文字幕午夜 | eeuss影院在线观看第一页 | 成人免费动作大片黄在线 | 一道本高清香蕉网 | 亚洲欧洲日产国码二区在线 | 致命弯道8在线观看高清免费观看 | 亚洲欧美日韩高清中文在线 | 一级毛片免费不卡直观看 | 向日葵视频app在线无限看免费 | 97在线观看免费 | 久久综合精品国产一区二区三区 | 人间正道是沧桑全集手机免费观看 | 免费99视频有精品视频高清 | 欧美视频一级 | 五月天婷婷丁香中文在线观看 | 久久国产精品久久国产片 | 日韩精品亚洲人成在线观看 | 国产手机看片 | 九九热在线精品视频 | 日本视频免费观看 | 精品国产一区二区麻豆 | 黄片毛片在线看 | 国产福利精品一区二区 | 国产精品不卡在线观看 | 免费va在线观看 |