產品詳情
簡單介紹：
Anti-ATF1抗體產品質量穩定，實驗效果明顯，貨期快，價格優惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-ATF1抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-ATF1
Cat. Number:
KL-0517R
Quantity size:
0.2ml
Concentration:
Anti-ATF1抗體1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Anti-ATF1抗體ATF1 (Activating Transcription Factor 1, TREB-36) is a member of the ATF/CREB family of basic region leucine-zipper (bZip) DNA-binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. The activation function of CRE-binding proteins may be modulated by phosphorylation of several kinases and is mediated by coactivators such as CREB-binding protein (CBP) and p300. ATF1 is a nuclear protein that binds DNA as a homodimer or as heterodimers with the inducible transcription factors CREB1 or CREM. Heterodimers appear to be stronger transcriptional activators than the homodimers. Tissue expression of ATF1 mRNA is widespread. Several isoforms of ATF1 arise by differential splicing. ATF1 mediates both Ca2+ and cAMP responses at several levels. It binds to the Tax-responsive element (TRE1) of the human T-cell lymphotropic virus type-I (HTLV1). ATF1 is detectable in metastatic melanoma cells and seems to contribute to their survival. A chimeric protein composed of the N-terminal domain of EWS (Ewing sarcoma oncogene) linked to the bZip domain of ATF1 is implicated in the rare malignant clear cell sarcoma of tendon sheath and aponeuroses (malignant melanoma of soft parts).
Also known as:
Anti-ATF1抗體Activating Transcription Factor1; TREB36 protein; ATF 1; ATF1 EWS fusion gene ATF1 FUS fusion gene; cAMP dependent transcription factor 1; Cyclic AMP dependent transcription factor ATF 1; Cyclic AMP dependent transcription factor ATF1; EWS AFT1; FUS ATF 1; RNA binding protein activating transcription factor 1 fusion protein; TREB 36; TREB36; ATF1_HUMAN.
Specificity:
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Rabbit Polyclonal IgG, affinity purified by Protein A.
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Reacts with: Human, Mouse, Rat, .
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Immunogen: KLH conjugated synthetic peptide derived from human ATF1.
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Predicted Molecular Weight: 29kDa.
Storage:
Anti-ATF1抗體Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
Anti-ATF1抗體WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.kl621Mu01 白介素1家族成員9(IL1F9)多克隆抗體 Polyclonal Antibody to Interleukin 1 Family, Member 9 (IL1F9)
kl624Hu01 107kDa肌醇多聚磷酸-4-磷酸酶Ⅰ型(INPP4A)多克隆抗體 Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)
kl624Mu01 107kDa肌醇多聚磷酸-4-磷酸酶Ⅰ型(INPP4A)多克隆抗體 Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)
kl630Hu01 泛素交叉反應蛋白(UCRP)多克隆抗體 Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP)
kl637Hu01 連接附著分子3(JAM3)多克隆抗體 Polyclonal Antibody to Junctional Adhesion Molecule 3 (JAM3)
kl643Mu01 EGF樣域蛋白7(EGFL7)多克隆抗體 Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7)
kl709Hu01 MARCKS相關蛋白(MARCKSL1)多克隆抗體 Polyclonal Antibody to MARCKS Related Protein (MARCKSL1)
kl761Hu01 氨酰tRNA合成酶復合多功能相互作用蛋白1(AIMP1)多克隆抗體 Polyclonal Antibody to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
kl761Mu01 氨酰tRNA合成酶復合多功能相互作用蛋白1(AIMP1)多克隆抗體 Polyclonal Antibody to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
kl763Hu01 黏病毒耐藥蛋白1(MX1)多克隆抗體 Polyclonal Antibody to Myxovirus Resistance 1 (MX1)
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.kl621Mu01 白介素1家族成員9(IL1F9)多克隆抗體 Polyclonal Antibody to Interleukin 1 Family, Member 9 (IL1F9)
kl624Hu01 107kDa肌醇多聚磷酸-4-磷酸酶Ⅰ型(INPP4A)多克隆抗體 Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)
kl624Mu01 107kDa肌醇多聚磷酸-4-磷酸酶Ⅰ型(INPP4A)多克隆抗體 Polyclonal Antibody to Inositol Polyphosphate-4-Phosphatase Type I 107kDa (INPP4A)
kl630Hu01 泛素交叉反應蛋白(UCRP)多克隆抗體 Polyclonal Antibody to Ubiquitin Cross Reactive Protein (UCRP)
kl637Hu01 連接附著分子3(JAM3)多克隆抗體 Polyclonal Antibody to Junctional Adhesion Molecule 3 (JAM3)
kl643Mu01 EGF樣域蛋白7(EGFL7)多克隆抗體 Polyclonal Antibody to EGF Like Domain Protein, Multiple 7 (EGFL7)
kl709Hu01 MARCKS相關蛋白(MARCKSL1)多克隆抗體 Polyclonal Antibody to MARCKS Related Protein (MARCKSL1)
kl761Hu01 氨酰tRNA合成酶復合多功能相互作用蛋白1(AIMP1)多克隆抗體 Polyclonal Antibody to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
kl761Mu01 氨酰tRNA合成酶復合多功能相互作用蛋白1(AIMP1)多克隆抗體 Polyclonal Antibody to Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1)
kl763Hu01 黏病毒耐藥蛋白1(MX1)多克隆抗體 Polyclonal Antibody to Myxovirus Resistance 1 (MX1)
