產(chǎn)品詳情
簡單介紹：
Anti-AT2R2抗體產(chǎn)品質量穩(wěn)定，實驗效果明顯，貨期快，價格優(yōu)惠，歡迎垂詢訂購！我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-AT2R2抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹：
Rabbit Anti-AT2R2
Cat. Number:
Anti-AT2R2抗體KL-2133R
Quantity size:
0.2ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Angiotensin II (Ang II) Anti-AT2R2抗體is an important physiological effector of blood pressure and volume regulation through vasoconstriction, aldosterone release, sodium uptake and thirst stimulation. Although Ang II interacts with two types of cell surface receptors, AT1 and AT2, most of the major cardiovascular effects seem to be mediated through AT1. Molecular cloning of the AT1 protein has shown it to be a member of the G protein-associated seven transmembrane protein receptor family. Ang II treatment of cells results in activation of several signal transduction pathways as evidenced by tyrosine phosphorylation of several proteins and induction of others. PLC?is phosphorylated after 30 seconds of treatment with Angiotensin II, indicating this as an early signal transduction event. Ang II treatment also stimulates phosphorylation of Shc, FAK and MAP kinases, and induces MKP-1, indicating stimulation of growth factor pathways. Ang II stimulation through AT1 has been shown to activate the JAK/Stat pathway involving a direct interaction between JAK2 and AT1 as demonstrated by coimmunoprecipitation. The AT1 receptor has no cytoplasmic kinase domain, but is able Anti-AT2R2抗體to function as a substrate for Src kinases and has several putative phosphorylation sites.
Also known as:
AGTR 2; AGTR2; Anti-AT2R2抗體AGTR-2; AGTR2_HUMAN; angiotensin II receptor type 2; Angiotensin II Type 2; Angiotensin II type-2 receptor; Angiotensin receptor 2; AT 2; AT2; AT2R2 ATGR 2; ATGR2; ATGR-2; MRX 88; MRX88; Type 2 angiotensin II receptor; Type-2 angiotensin II receptor.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Dog, Pig, Horse, Sheep, .
●
Immunogen: KLH conjugated synthetic peptide derived from human angiotensin II receptor type 2.
●
Predicted Molecular Weight: 41kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other Anti-AT2R2抗體applications.
Optimal working dilutions must be determined by the end user.
Not yet tested in other Anti-AT2R2抗體applications.
Optimal working dilutions must be determined by the end user.
kl054Ra01 胰島素樣生長因子結合蛋白3(IGFBP3)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 3 (IGFBP3)
kl055Bo01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl055Cp01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl055Ga01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl055Hu01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl055Mu01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl055Po01 胰島素樣生長因子結合蛋白4(IGFBP4)多克隆抗體 Polyclonal Antibody to Insulin Like Growth Factor Binding Protein 4 (IGFBP4)
kl056Bo01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Ca01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Cp01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Eq01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Ga01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Gu01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Hu01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Mu01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Po01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Ra01 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
kl056Rb51 白介素10(IL10)多克隆抗體 Polyclonal Antibody to Interleukin 10 (IL10)
