產品詳情
簡單介紹:
Anti-phospho-PFKL /PFK1(Ser775)抗體產品質量穩定,實驗效果明顯,貨期快,價格優惠,歡迎垂詢訂購!我公司長期供應**組化抗體、WB抗體、**組化試劑盒和抗體試驗所需全部相關試劑、熒光標記抗體、單克隆抗體、多克隆抗體、各種標記的二抗IgG/IgM/IgD/IgA等科研實驗抗體。Anti-phospho-PFKL /PFK1(Ser775)抗體用于**組化實驗,WB實驗,相應的標記抗體有HRP標記抗體,FITC標記,BIO等。
詳情介紹:
Rabbit Anti-phospho-PFKL /PFK1(Ser775)
Cat. Number:
Anti-phospho-PFKL /PFK1(Ser775)抗體KL-4027R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
Phosphofructokinases (PFKs) are regulatory glycolytic enzymes that catalyze the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate. Mammalian PFK is a tetramer made up of diverse combinations of three isoenzymes: muscle (PFK-1), liver (PFKL) and platelet (PFKP). PFKL (phosphofructokinase, liver), Anti-phospho-PFKL /PFK1(Ser775)抗體also referred to as PFK-B (Phosphofructo-1-kinase isozyme B), phosphofructokinase 1 or phosphohexokinase, predominates in organs with active gluconeogenesis, such as liver and kidney. Overexpression of PFKL in transgenic mice results in a diminished glucose-induced insulin response, which suggests that PFKL may play a role in glucose-induced insulin secretion. PFKL is expressed at high levels in Down's syndrome (DS) patients, suggesting a possible role for PFKL in the pathogenesis of DS.
Also known as:
PFKL (phospho S775); PFKL (phospho Ser775); p-PFKL (Ser775); ATP-dependent 6-phosphofructokinase, liver type;Anti-phospho-PFKL /PFK1(Ser775)抗體 ATP-PFK; PFK-L; 6-phosphofructokinase type B; Phosphofructo-1-kinase isozyme B; PFK-B; Phosphohexokinase; Phosphohexokinase; PFKAL_HUMAN。
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Human, Mouse, Rat, Pig, Cow, Horse, Sheep, .
●
Immunogen: KLH conjugated Anti-phospho-PFKL /PFK1(Ser775)抗體Synthesised phosphopeptide derived from human PFKL around the phosphorylation site of Ser775.
●
Predicted Molecular Weight: 86kDa.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-phospho-PFKL /PFK1(Ser775)抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-phospho-PFKL /PFK1(Ser775)抗體
Optimal working dilutions must be determined by the end user.