產(chǎn)品詳情
簡(jiǎn)單介紹:
Anti-Phosphoserine/threonine抗體產(chǎn)品質(zhì)量穩(wěn)定,實(shí)驗(yàn)效果明顯,貨期快,價(jià)格優(yōu)惠,歡迎垂詢訂購(gòu)!我公司長(zhǎng)期供應(yīng)**組化抗體、WB抗體、**組化試劑盒和抗體試驗(yàn)所需全部相關(guān)試劑、熒光標(biāo)記抗體、單克隆抗體、多克隆抗體、各種標(biāo)記的二抗IgG/IgM/IgD/IgA等科研實(shí)驗(yàn)抗體。Anti-Phosphoserine/threonine抗體用于**組化實(shí)驗(yàn),WB實(shí)驗(yàn),相應(yīng)的標(biāo)記抗體有HRP標(biāo)記抗體,FITC標(biāo)記,BIO等。
詳情介紹:
Rabbit Anti-Phosphoserine/threonine
Cat. Number:
Anti-Phosphoserine/threonine抗體KL-11994R
Quantity size:
0.1ml
Concentration:
1mg/ml Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Background:
A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized Anti-Phosphoserine/threonine抗體by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The Phospho-(Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.
Also known as:
phospho-Ser/Phospho-Thr; pS/pT; p-S/p-T; Anti-Phosphoserine/threonine抗體pSER/pThr; p-SER/p-Thr; p-Sp-T.
Specificity:
●
Rabbit Polyclonal IgG, affinity purified by Protein A.
●
Reacts with: Phosphoserine/threonine.
●
Immunogen: KLH conjugated synthesised Anti-Phosphoserine/threonine抗體phosphopeptide contain Phosphoserine and Phosphothreonine.
Storage:
Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).
Application:
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
Not yet tested in other applications. Anti-Phosphoserine/threonine抗體
Optimal working dilutions must be determined by the end user.
Not yet tested in other applications. Anti-Phosphoserine/threonine抗體
Optimal working dilutions must be determined by the end user.